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Discontinuation of Supply- Nitrofurantoin

posted Mar 12, 2017, 8:05 PM by Izam Ezri Mohd Zakaria   [ updated Mar 12, 2017, 8:05 PM by Ho Ai Wui ]
9th March 2017 (Circular No. SP PPUM:  96 /2017):

Apotex Inc. Canada, the sole supplier of Nitrofurantoin Tablets in Malaysia, has discontinued manufacturing the medication.

Furthermore, application by UMMC to import from another supplier had been rejected by the Malaysian Drug Control Authority citing that there are other suitable antibiotics available for treating the same type of infections that nitrofurantoin is used for.
Below are antibiotics suggested by UMMC's Antibiotic Guideline for replacing nitrofurantoin:

 Acute Uncomplicated cystitis Co-amoxiclav  625 mg PO q12H
Cefalexin 500 mg PO q8H (for pregnancy)
 Cefuroxime 250 mg PO q12H
 Asymptomatic Bacteriuria Cefalexin 500mg PO q8H (for pregnancy) Trimethoprim / Sulfamethoxazole 1 tab PO q12H for 3 days (if no culture)