Latest Medication News

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Medication Supply Disruption

posted Jun 12, 2018, 1:05 AM by Chong Ching Wern   [ updated Jun 12, 2018, 1:05 AM ]

12 June 2018 (Circular No. SP PPUM: 217/2018):

The following medications will be facing supply disruptions:

No.

Name of Medication

Formulary Category

Cause / Action by Pharmacy

Estimated Stock Recovery

Alternative Medication


1)

Fentanyl 100mcg/2mL Injection

Standard Formulary

· Raw material supply issues by Duopharma (M) Sdn. Bhd.

· Pharmacy Department has a balance stock of  about 1500 ampoules only.

August 2018.

Consider use of other medications which are available in our Standard Formulary

2)

Dexamethasone 8mg Injection (For IT use)



Standard Formulary

· Production ceased.

· Raw materials were found not suitable for Intrathecal preparations. 


N/A

Consider use of IT Hydrocortisone Sodium Succinate 25mg/0.5mL Injection prepared by our Manufacturing Pharmacy.

3)

Potassium Dihydrogen Phosphate 10mmol/10mL Injection

Standard Formulary

· Stock supply delivery delay by Pfizer (M) Sdn. Bhd.



Until further notice.

None, Pfizer (M) Sdn. Bhd. is the sole manufacturer of the medication.

4)

Lidocaine 1% Injection


Standard Formulary

· Stock supply issues by Pfizer (M) Sdn. Bhd.

· Remaining stocks will solely be used for cases which require intravenous administration only. 


N/A

Ward stock supplies will be switched to Lidocaine 2% Injection.

Medication Supply Disruption

posted May 29, 2018, 8:58 PM by Chong Ching Wern   [ updated May 29, 2018, 8:58 PM ]

28 May 2018 (Circular No. SP PPUM: 196/2018): 

The following medications will be facing supply disruptions:

No.

Name of Medication

Formulary Category

Cause / Action by Pharmacy

Estimated Stock Recovery

Alternative Medication


1)

Albumin Human 20%



Standard Formulary

· Production issues by Grifols Malaysia Sdn. Bhd.

· Usage is only reserved for critical cases including 'replacement after large volume parecentesis'.


Until further notice.

None, other companies are also experiencing stock issues.

Please contact Inpatient Pharmacy first for elective surgeries. 

2)

Co-Trimoxazole 480mg Injection



Standard Formulary

· Production issues by Pfizer (M) Sdn. Bhd.

· Supply limited to patients who are unable to tolerate oral therapy. 


August 2018.

Consider use of Co-Trimoxazole 480mg Tablet in view of its oral bio-availability is comparable to the injection.

3)

Ketamine 500mg/10mL Injection

Standard Formulary

· Production issues by Duopharma (M) Sdn. Bhd. and Pharmaniaga Sdn. Bhd.



Until further notice.

Consider use of other anaesthesias which are available in our Standard Formulary.

4)

Prothrombin Complex (Factor II, VII, IX, X) (Octoplex)


Standard Formulary

· Stock supply issues by Pharmaniaga Marketing Sdn. Bhd.

Early July 2018.

None.

5)

Ropivacaine 150mg/20mL Injection (Naropin)

Standard Formulary

· Stock supply issues by Aspen Malaysia Sdn. Bhd.

· Supply of medication will be controlled by Inpatient Pharmacy. 


Until further notice.

None, will notify when all stocks have been used up.

6)

Dosulepin 75mg Tablet

Standard Formulary

· Production issues by all distributors for this medication in Malaysia.


Until further notice.

Dosulepin 25mg Tablet will be used.

7)

Cisplatin 50mg/50mL Injection

Standard Formulary

· Production issues by Pfizer (M) Sdn. Bhd. and other manufacturers.

· Sorting out supplies from companies that still have leftover stocks.


Until further notice.

None, doctors are encouraged not to start new patients on this medication.

Temporary Medication - Fenofibrate 160mg Tablet

posted Apr 17, 2018, 7:18 PM by Chong Ching Wern   [ updated Apr 17, 2018, 7:33 PM ]

17 April 2018 (Circular No. SP PPUM: 134/2018):
We are pleased to inform you that Pharmaforte have taken the initiative to supply us with Apo-Fenofibrate SP 160mg Tablet as an alternative to our Apo-Fenofibrate 200mg Capsule which is currently facing supply disruptions.

Both medications are equivalent and it was agreed by our Specialists to have a direct conversion:

1 capsule of Apo-Fenofibrate 200mg =1 tablet of Apo-Fenofibrate SP 160mg

Please do note that this Apo-Fenofibrate SP 160mg will be a temporary replacement medication until the supply has resumed.
APO-Fenofibrate SP 160mg Tablets

Formulary Category Change - Lamotrigine, Levitiracetam, Topiramate

posted Apr 17, 2018, 6:33 PM by Chong Ching Wern   [ updated Apr 17, 2018, 6:39 PM ]

17 April 2018 (Circular No. SP PPUM: 132/2018):
Based on the decision of UMMC's Tender Board on 23 November 2016 (Circular No. SP PPUM: 15/2017 dated 10 January 2017), there was a change of category of the following medications from Standard Formulary to Special Formulary:
      1. Lamotrigine 50mg Tablet
      2. Lamotrigine 100mg Tablet
      3. Levetiracetam 250mg Tablet
      4. Levetiracetam 500mg Tablet
      5. Levetiracetam 1000mg Tablet
      6. Topiramate 25mg Tablet
      7. Topiramate 50mg Tablet
      8. Topiramate 100mg Tablet
However, following the agreement from our Specialists to use generic medications in treating patients, the change in formulary category from Standard Formulary to Special Formulary is cancelled.

These medications will be remained as Standard Formulary.

Medication Supply Disruption

posted Apr 9, 2018, 7:06 PM by Chong Ching Wern   [ updated Apr 9, 2018, 7:06 PM ]

9 April 2018 (Circular No. SP PPUM: 120/2018):

The following medications will be facing supply disruptions:

No.

Name of Medication

Formulary Category

Cause / Action by Pharmacy

Estimated Stock Recovery

Alternative Medication


    1)

Albumin Human 20%



Standard Formulary

· Production issues by Grifols Malaysia Sdn. Bhd.

· Usage is only reserved for critical cases.

Mid April 2018

None, other companies are also experiencing stock issues.

    2)

Co-Careldopa 25mg / 100mg (Sinemet) Tablet



Standard Formulary

· Production issues by Menarini Singapore Pte. Ltd.

· Sort out supply from other suppliers.

Late June 2018

None, other companies are also experiencing stock issues.

    3)

Methotrexate 2.5mg Tablet

Standard Formulary

· Delay in stock delivery issues by Pfizer (M) Sdn. Bhd.

· Restricted to monthly supply only.

January 2019

None, Pfizer (M) Sdn. Bhd. is the sole manufacturer of the medication.

    4)

Potassium Dihydrogen Phosphate 10mmol/10mL Injection



Standard Formulary

· Delay in stock delivery issues by Pfizer (M) Sdn. Bhd.

· Ward stock supply will be temporarily ceased and prescription will be required for every supply.

Early June 2018

Consider use of
Neutral Phosphate Oral Solution:
Every 10mL of Neutral Phosphate Solution contains sodium 9.7mmol, phosphate 5.4mmol (elemental phosphate 166mg).

Discontinued Medication - Premelle 2.5mg Tablet

posted Apr 9, 2018, 12:40 AM by Chong Ching Wern   [ updated Apr 9, 2018, 12:41 AM ]

6 April 2018 (Circular No. SP PPUM: 119/2018):
Name of Medication: Oestrogen 625mcg + Medroxyprogesterone 2.5mg
Brand: Premelle
Form: Tablet
Company: Pfizer (Malaysia) Sdn. Bhd.
Formulary Category: Standard

Pfizer (Malaysia) Sdn. Bhd. had discontinued the production of Premelle 2.5mg tablets since October 2017.

However, doctors can still start or continue the same treatment regimen by prescribing the medications separately, both which are of Standard Formulary medications:

Conjugated oestrogen 625mcg once daily 

AND

Medroxyprogesterone 2.5mg once daily
Premelle 2.5mg Tablets

Formulary Category Change - Imipenem-Cislatin Combo Injection

posted Mar 13, 2018, 9:07 PM by Chong Ching Wern   [ updated Mar 13, 2018, 9:08 PM ]

13 March 2018 (Circular No. SP PPUM: 90/2018):
Name of Medication: Imipenem 500mg Cislatin 500mg
Form: Injection
Formulary Category: Non-Formulary

Based on the outcome of the Drug and Therapeutic Subcommittee Meeting (Bil. 1/2018) held on 12 March 2018, there will be a change in the formulary category for the medication Imipenem 500mg Cislatin 500mg Injection to Non-Formulary.

Suggested alternative to this medication is Meropenem 1g and 500mg Injection as their formulary category remain unchanged.

What does Non-Formulary means?
This means that if patients are being prescribed on this medication, the medication is not readily available in UMMC and they will have to purchase it from other retail pharmacies apart from UMMC.
Imipenem 500mg Cislatin 500mg Injection

Medication Supply - Disruption of Co-Trimoxazole 480mg Injection Supply

posted Mar 13, 2018, 8:39 PM by Chong Ching Wern   [ updated Mar 13, 2018, 8:59 PM ]

13 March 2018 (Circular No. SP PPUM: 89/2018):
Name of Medication: Co-Trimoxazole 480mg
Form: Injection
Company: Pfizer (Malaysia) Sdn. Bhd.
Formulary Category: Standard Formulary

The manufacturer of Co-Trimoxazole 480mg Injection, Pfizer (Malaysia) Sdn. Bhd., is currently facing supply disruptions and the supply is expected to resume by end of May 2018.

The current stock level is at its minimal (about 200 ampoules) and will strictly be used for patients who are unable to tolerate oral therapy.

Doctors can prescribe Co-Trimoxazole 480mg Tablet as an alternative if the use of this medication is required since the oral bio-availability is comparable to the injection.

This supply disruption is beyond UMMC's control and we apologize for any inconveniences caused.
Co-Trimoxazole 480mg Injection

Medication Supply - Disruption of Human Albumin 25% Injection Supply

posted Mar 4, 2018, 6:31 PM by Chong Ching Wern   [ updated Mar 4, 2018, 6:31 PM ]

1st March 2018 (Circular No. SP PPUM: 82/2018):
Name of Medication: Albumin 25%
Brand: Albutein
Form: Injection
Company: Grifols Malaysia Sdn. Bhd.
Formulary Category: Standard Formulary

The manufacturer of Albumin 25% Injection, Grifols Malaysia Sdn. Bhd., is currently facing supply disruptions and the supply is expected to resume by mid March 2018.

The current stock level is at its minimal and will be only used for indicated situations such as 'replacement after large volume paracentesis'.

This supply disruption is beyond UMMC's control and we apologize for any inconveniences caused.
Albumin 25% Injection

Medication Supply - Disruption of Human Normal Immunoglobulin 2.5 gm Injection Supply

posted Mar 4, 2018, 6:02 PM by Chong Ching Wern   [ updated Mar 4, 2018, 6:08 PM ]

1st March 2018 (Circular No. SP PPUM: 81/2018):
Name of Medication: Human Normal Immunoglobulin 2.5 gm
Form: Injection
Company: Grifols Malaysia Sdn. Bhd.
Formulary Category: Standard Formulary

The manufacturer of Human Normal Immunoglobulin 2.5 gm Injection, Grifols Malaysia Sdn. Bhd., is currently facing supply disruptions and the supply is expected to resume by mid March 2018.

The current stock level is at its minimal (about 50 vials) and will be only used for emergency and critical situations only.

This supply disruption is beyond UMMC's control and we apologize for any inconveniences caused.
Human Normal Immunoglobulin 2.5 gm Injection

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