Drug & Therapeutics Subcommittee



D&T Subcommittee Meeting Bil. 02/2019

posted Jul 1, 2019, 6:06 PM by Chong Ching Wern   [ updated Jul 1, 2019, 6:16 PM ]


No.

Drug Name

Decision

1)

Propafenone 150mg Tablet

(Rytmonorm)

Agreed to accept as Special Formulary.

2)

Flecainide 100mg Tablet

(Tambocor)

Rejected as Special Formulary.

Propafenone was accepted as Special Formulary for the same indication.

3)

Deferasirox 90mg Tablet

Deferasirox 360mg Tablet

(Exjade)

Rejected as Standard Formulary.

Suggest requestor to apply for extra funding from Jawatankuasa Pengurusan Kewangan dan Akaun (JPKA) for additional subsidy for five patients.

4)

Flurbiprofen 4mg Patch

(Acustop Cataplasma)

Rejected as Special Formulary.

Availability of Diclofenac Gel and Ketoprofen Gel in the UMMC formulary and readily available in retail pharmacies.

5)

Paroxetine 25mg CR Tablet

(Seroxat)

Agree to delete from the UMMC formulary.

To use generic option as first choice and was agreed by Psychiatric Team to switch to Apo-Paroxetine 20mg Tablet.

6)

Montelukast 4mg Tablet

(Singulair)

Agree to delete from the UMMC formulary.

Slow movement and stocks were expired. Availability of Montelukast 4mg Granules in the UMMC formulary.

7)

Telbivudine 600mg Tablet

(Sebivo)

Agree to delete from the UMMC formulary.

Company discontinuation.

8)

Tinzaparin 4500units Injection

(Innohep)

Agree to delete from the UMMC formulary.

Company discontinuation.

9)

Vitamin B (B1, B2, B6) Injection 

(Becolim)

Agree to delete from the UMMC formulary. 

Company discontinuation. Availability of Vitamin B and C Injection in the UMMC formulary.

10)

Olodaterol 2.5mcg Inhalation Solution 

(Striverdi Respimat)

Agree to delete from the UMMC formulary.

Company discontinuation. Availability of Spiriva Respimat and Spiolto Respimat in the UMMC formulary.

11)

Oxybutinin 5mg Tablet

(Voxytane)

Agree to delete from the UMMC formulary.

Company discontinuation and was agreed by Peadiatric Surgery Team.

12)

Dulaglutide 0.75mg Injection

Dulaglutide 1.5mg Injection

(Trulicity)

Rejected as Special Formulary.

Dulaglutide’s Cardiovascular Outcome Trial (CVOT) published: Dulaglutide reduced cardiovascular outcomes in patients with or without previous cardiovascular disease. 

Costs more than Liraglutide 1.2mg once daily (with CVOT) and Exenatide 2mg once weekly.



Disclaimer: 

For new drug request, physical stock availability will depend on procurement processes. 

Tender items will take about 3-6 months, non tender items will take about 1-3 months. 

Online formulary will be updated once physical stock is available or has depleted in UMMC Pharmacy.

D&T Subcommittee Meeting Bil. 01/2019

posted Apr 15, 2019, 11:48 PM by Chong Ching Wern   [ updated Apr 15, 2019, 11:48 PM ]


No.

Drug Name

Decision

1)

Rufinamide 200mg Tablet

(Inovelon)

Agreed to accept as Special Formulary (upon request).

2)

Yellow Fever Vaccine Injection

(Stamaril)

Agree to accept as Special Formulary (non-claimable).

3)

Dapagliflozin 10mg Tablet

(Forxiga)

Rejected to add Cardiologists as prescriber, to maintain current restriction.

4)

Baricitinib 4mg Tablet

(Olumiant)

Rejected as Special Formulary.

Availability of Tofacitinib 5mg Tablet in the UMMC formulary.

Suggest to apply to use using BUK on named patient basis.

5)

Esomeprazole 20mg MUPS Tablet

Esomeprazole 40mg MUPS Tablet

Multiple Unit Pellet System

(Nexium / Axiago)

Agree to accept as Standard Formulary to replace Omeprazole 2mg/mL Syrup.

6)

Aripiprazole 400mg Prolonged Release Injection

(Abilify Maintena)

Agree to accept as Special Formulary.

7)

Liothyronine 100mcg Injection

Agree to delete from the UMMC formulary.

Availability of Levothyroxine 200mcg Injection in the UMMC formulary.

8)

Polymixin B Neomycin Hydrocortisone Ear Drops

(Pocin)

Agree to delete from the UMMC formulary.

Ototoxicity due to Neomycin component and removal from APPL contract list.

9)

Varenicline 1mg Tablet

(Champix)

Agree to delete from the UMMC formulary.

Closure of Smoking Cessation Clinic, no prescriptions seen since 2016, slow movement and easily available in community pharmacies.

10)

Varenicline 0.5mg Tablets x 11

Varenicline 1mg Tablets x 14

(Champix Starter Pack)

Agree to delete from the UMMC formulary.

Closure of Smoking Cessation Clinic, no prescriptions seen since 2016, slow movement and easily available in community pharmacies.

11)

Clodronate Sodium 800mg Tablet

(Bonefos)

Agree to delete from the UMMC formulary.

Company discontinuation.

12)

Isotretinoin 10mg Capsule

(Roaccutane)

Rejected to delete from the UMMC formulary, to maintain current restriction.

13)

Isotretinoin 20mg Capsule

(Roaccutane)

Rejected to delete from the UMMC formulary, to maintain current restriction.

14)

Dulaglutide 0.75mg Injection

Dulaglutide 1.5mg Injection

(Trulicity)

Pending press release on cardiovascular safety outcome trial in June 2019.

Costs more than existing agents available in the UMMC formulary.

Suggest to review pricing.



Disclaimer:

For new drug request, physical stock availability will depend on procurement processes.

Tender items will take about 3-6 months, non tender items will take about 1-3 months.

Online formulary will be updated once physical stock is available or has depleted in UMMC Pharmacy.

D&T Subcommittee Meeting 10 December 2018

posted Jan 21, 2019, 6:55 PM by Chong Ching Wern   [ updated Jan 21, 2019, 6:55 PM ]


No.


 Drug Name

 Decision
 
 1)

Posaconazole 100mg M/R Tablet
(Noxafil)


Agreed to accept as Special Formulary to replace Posaconazole 40mg/mL Suspension.
 
 
 2)

Tenofovir Disoproxil Fumarate 300mg Emtricitabine 200mg Efavirenz 600mg Tablet


Agree to accept as Standard Formulary as an add-on to currently available antiretroviral agents in the UMMC's Formulary.

 
 3)

Brinzolamide 1% Brimonidine 0.2% Ophthalmic Suspension
(Simbrinza)


Agree to accept as Special Formulary.

 
 4)

Pimecrolimus 1% Cream
(Elidel)

Agree to accept as Special Formulary for mild to moderate atopic dermatitis (Dermatologists only).

 
 5)

Aripiprazole 400mg Prolonged Release Injection
(Abilify Maintena)
 

Rejected as Special Formulary.

 
 6)

Citrate Solution (5L)
(Prismocitrate 18/0)

Agree to accept as Standard Formulary.
 
 7)

Rilpivirine 25mg Tablet 
(Edurant)

Rejected as Special Formulary.
Costs more than existing agents available in the UMMC's Formulary
Available in UMSC for purchase. 
 
 8)

Liraglutide 1.8mg Injection 
(Victoza)

Rejected to add Cardiologists as prescribers, to maintain current restriction.
There are other existing oral anti-diabetes agents that Cardiologists can prescribe at a lower cost in the UMMC's Formulary.

 
 9)

 Alteplase 50mg Injection
 

Acknowledged on the agreement of Pharmacy Department  to increase to 30 sets per year (effective October 2018).

 
10)

Nicotine 10mg Patch
(Nicorette)
 

Agree to delete from the UMMC's formulary.
Slow moving and stocks expired.

 
11)

 Nicotine 15mg Patch
(Nicorette)
 

Agree to delete from the UMMC's formulary. 
Slow moving and stocks expired.

 
12)

 Nicotine 25mg Patch
(Nicorette)
 

Agree to delete from the UMMC's formulary. 
Slow moving and stocks expired.

 
13)

Afatinib 50mg Tablet
(Giotrif)
 

Agree to delete from the UMMC's formulary.
Company discontinuation. 
Availability of 30mg and 40mg preparations in the UMMC's Formulary.

 
14)

Dronedarone 400mg Tablet
(Multaq)
 

Agree to delete from the UMMC's formulary.
Company discontinuation.

 
15)

Efavirenz 200mg Tablet
(Stocrin)


Agree to delete from the UMMC's formulary.
Company discontinuation.
Availability of Efavirenz 600mg Tablet preparation in the UMMC's Formulary.

 
16)

Vardenafil 10mg Tablet
(Levitra)
 

Agree to delete from the UMMC's formulary.
Availability of alternatives in the UMMC's Formulary.

 
17)

Vardenafil 20mg Tablet 
(Levitra)
 

Agree to delete from the UMMC's formulary. 
Availability of alternatives in the UMMC's Formulary.

 
18)

Strontium Ranelate 2gm Powder
(Protaxos)
 

Agree to delete from the UMMC's formulary. 
Company discontinuation.

 
19)

Buprenorphine 10mg Patch
(Sovenor)
 

Agree to delete from the UMMC's formulary. 
Company discontinuation. 
Availability of Buprenorphine 5mg Patch preparation in the UMMC's Formulary.

 
20)

Lamivudine 100mg Tablet
(Zeffix)
 

Agree to delete from the UMMC's formulary.
Slow moving and as per agreement by Gastroenterology Team.
Availability of alternatives in the UMMC's Formulary.

 
21)

Adefovir 10mg Tablet
(Hepsera)
 

Agree to delete from the UMMC's formulary. 
Slow moving and as per agreement by Gastroenterology Team. 
Availability of alternatives in the UMMC's Formulary.

 
22)

Isotretinoin 10mg Capsule
(Roaccutane)
 

Pharmacy to obtain consent from Dermatology Team before deleting from Special Formulary, to maintain current restriction.

 
23)

Isotretinoin 20mg Capsule
(Roaccutane)
 

Pharmacy to obtain consent from Dermatology Team before deleting from Special Formulary, to maintain current restriction.

 
24)

Interferon Alfa-2B 18 million units Injection
(Intron A)
 

Agree to delete from the UMMC's formulary. 
Company discontinuation.

 
25)

Interferon Alfa-2B 30 million units Injection
(Intron A) 
 

Agree to delete from the UMMC's formulary. 
Company discontinuation.

 
26)

Abciximab 10mg/mL Injection
(Repro)
 

Agree to delete from the UMMC's formulary.
Company discontinuation.

 
27)

Posaconazole 40mg/mL Suspension
(Noxafil)
 

Agree to delete from the UMMC's formulary.  
Replaced by Posaconazole M/R Tablet.



Disclaimer: 
For new drug request, physical stock availability will depend on procurement processes. 
Tender items will take about 3-6 months, non tender items will take about 1-3 months. 
Online formulary will be updated once physical stock is available or has depleted in UMMC Pharmacy.

D&T Subcommittee Meeting 24 September 2018

posted Oct 15, 2018, 12:58 AM by Chong Ching Wern   [ updated Oct 15, 2018, 1:14 AM ]


 No.


 Drug Name

 Decision
 
 1)

 Oxycodone Hydrochloride 10mg/mL Injection
 (Oxynorm)


 Rejected as UMMC Formulary. 
 Available in UMSC for purchase.
 
 2)

 Alirocumab 75mg Injection
 Alirocumab 150mg Injection 
 (Praluent)


 Rejected as Special Formulary.
 Apply for use via BUK form on named patient basis.

 
 3)

 Liraglutide 1.8mg Injection 
 (Victoza)

 To be discussed again in next D&T Meeting in December    2018.
 
 4)

 Linagliptin 5mg Tablet 
 (Trajenta)

 Agreed to to switch Sitagliptin (350 subsidy cards) to   Linagliptin (350 subsidy cards) in Outpatient Pharmacy in   the next tender due in 2020.

 
 5)

 Macitentan 10mg Tablet 
 (Opsumit)
 

 Agreed to accept Macitentan as Special Formulary to   replace Bosentan 125mg Tablet (Tracleer).

 
 6)

 Glycopyrronium 50mcg Inhalation Capsule
 (Seebri Breezhaler)

 Rejected as Special Formulary.
 Available in UMSC for purchase.
 
 7)

 Celecoxib 200mg Capsule
 (Celebrex)

 Agreed to supply Celecoxib to Orthopedics in-patients for   acute pain management of fractures pre-operation and
 post-operation up to maximum of 20 capsules in total. 
 
 8)

 Dapagliflozin 10mg Tablet
 (Forxiga)

 Rejected to add new prescribers, to maintain current   restriction.
 
 9)

 Ketosteril Tablet
 

 No new patients with immediate effect.
 Pharmacy to continue supplying for existing 164 AP patients   until 31 December 2019.
 All patients to pay full cost and not claimable effective 1   January 2020.

 
10)

 Olodaterol 2.5mcg Inhalation Solution
 (Striverdi Respimat)
 

 Agreed to change from UMMC Formulary to Special   Formulary.

 
11)

 Tacrolimus 0.5mg Capsule
 Tacrolimus 1mg Capsule
 (Prograf)
 

 Rejected to add 20 subsidy cards for the indication of Lupus   Nephritis, to maintain current restriction.

 
12)

 Vildagliptin 50mg Tablet
 (Galvus)
 

 Deleted.

 
13)

 Vildagliptin 50mg Metformin 850mg Tablet
 Vildagliptin 50mg Metformin 1000mg Tablet
 (GalvusMet)
 

 Deleted.

 
14)

 Sitagliptin 100mg Tablet
 (Januvia)
 

 Deleted.
 To be replaced by Linagliptin in the next tender once current   tender ends in year 2020.

 
15)

 Sitagliptin 50mg Metformin 850mg Tablet
 Sitagliptin 50mg Metformin 1000mg Tablet
 (JanuMet)


 Deleted.

 
16)

 Bosentan 125mg Tablet
 (Tracleer)
 

 Deleted.

 
17)

 Sertraline 50mg Tablet
 (Zoloft)
 

 Deleted.

 
18)

 Alendronate 70mg Cholecalciferol 5600iu Tablet   (Fosamax Plus)
 

 Deleted.

 
19)

 Etoposide 50mg Capsule
 

 Deleted.

 
20)

 Granisetron 1mg Tablet
 

 Deleted.
 
21)

 Pilocarpine 2% Eye Drop
 Pilocarpine 4% Eye Drop
 

 Deleted.


Disclaimer: 
For new drug request, physical stock availability will depend on procurement processes. 
Tender items will take about 3-6 months, non tender items will take about 1-3 months. 
Online formulary will be updated once physical stock is available or has depleted in UMMC Pharmacy.

D&T Subcommittee Meeting 4 June 2018

posted Jun 24, 2018, 6:14 PM by Chong Ching Wern   [ updated Jun 24, 2018, 6:15 PM ]

 
 No.


 Drug Name

 Decision
 
 1)

 Fluticasone Propionate 125mcg Formoterol 5mcg
 Inhaler
 Fluticasone Propionate 250mcg Formoterol 10mcg
 Inhaler
 (Flutiform)


 Accepted only one strength (Fluticasone Propionate 125mcg
 Formoterol 5mcg 
Inhaler) as Special Formulary.
 
 2)

 Benzydamine Hydrochloride 0.3% Spray 
 (Difflam Forte Throat Spray)

 Rejected to add new prescribers, to maintain current
 restrictions.

 
 3)

 Ibuprofen 20mg/mL Oral Suspension

 Accepted as Standard Formulary for paediatrics with Patent 
 Ductus Arteriosus (PDA) only.
 
 4)

 Desmopressin 200mcg Tablet 
 (Minirin)

 Agreed to add Paediatric Nephrologist as prescriber for
 paediatrics with Primary Nocturnal Enuresis (PNE) only.

 
 5)

 Dinoprostone 10mg Vaginal Delivery System
 (Cervidil)
 

 Rejected.

 
 6)

 Rituximab 1400mg/11.7mL Solution for SC
 Injection
 (MabThera SC)


 Accepted as Special Formulary (upon request).
 
 7)

 Fentanyl 100mcg Sublingual Tablet
 Fentanyl 200mcg Sublingual Tablet
 Fentanyl 400mcg Sublingual Tablet
 (Abstral)
 

 Accepted as Special Formulary (200 and 400mcg
 upon request).

 
 8)

 Dolutegravir 50mg Tablet 
 (Tivicay)

 Agreed to have 40 subsidy cards.
 Changed Post Exposure Prophylaxis (PEP) regimen to
 Tenofovir / Emtricitabine + Dolutegravir.

 
 9)

 Lopinavir 200mg Ritonavir 50mg Tablet 
 (Kaletra)
 

 Agreed to change 20 Kaletra's subsidy cards to 20
 Dolutegravir's subsidy cards.
 Total Kaletra's subsidy cards will now be 130. (Refer Item 8)

 
10)

 Raltegravir 400mg Tablet 
 (Tivicay)
 

 Agreed to replace all 20 Raltegravir's subsidy cards with 20
 Dolutegravir's subsidy cards. (Refer Item 8)

 
11)

 Beclometasone 100mcg Formoterol 6mcg Inhaler
 (Foster)
 

 Deleted.

 
12)

 Nimodipine 30mg Tablet 
 (Nimotop)
 

 Deleted.

 
13)

 Etoricoxib 60mg Tablet 
 (Arcoxia)
 

 Deleted.

 
14)

 Esomeprazole 40mg Injection
 (Nexium)
 

 Deleted.

 
15)

 Lercanidipine 10mg Tablet
 (Zanidip)  
 

 Deleted.

 
16)

 Asenapine 5mg Dispersible Wafer
 (Saphris)
 

 Deleted.

 
17)

 Pentosan Polysulfate 100mg Capsule
 (Elmiron)
 

 Deleted.

 
18)

 Amoxicillin 1000mg Tablet 
 (Ospamox)
 

 Deleted.

 
19)

 Levocetirizine 5mg Tablet
 (Xyzal)
 

 Deleted.

 
20)

 Fluconazole 150mg Capsule
 (Diflucan)
 

 Deleted.

 
21)

 Carboxymethycellulose 0.5% Eye Drop
 (Optive Advanced)
 

 Deleted.

 
22)

 Ethinylestradiol 20mcg Desogestrel 150mcg Tablet
 (Mercilon)
 

 Deleted.

 
23)

 Chlorhexidine 0.015% Cetrimide 0.15% Irrigation
 Solution (30mL)
 

 Deleted.

 
24)

 Ambroxol 30mg Tablet
 (Mucosolvan)
 

 Deleted.

 
25)

 Paracetamol 500mg Injection
 (Paracetamol Kabi)
 

 Deleted.


Disclaimer: 
For new drug request, physical stock availability will depend on procurement processes. 
Tender items will take about 3-6 months, non tender items will take about 1-3 months. 
Online formulary will be updated once physical stock is available or has depleted in UMMC Pharmacy.

D&T Subcommittee Meeting 12 March 2018

posted Jun 17, 2018, 7:26 PM by Chong Ching Wern   [ updated Jun 19, 2018, 7:51 PM ]

 
 No.


 Drug Name

 Decision
 
 1)

 Diacerein 50mg Capsules
 (Artrodar)


 Rejected.

 
 2)

 Fosfomycin Trometamol 3gm Sachet
 (Monurol)


 Rejected.


 
 3)

 Interferon Alfa 2A 135mcg and 180mcg Injection 
 (Pegasys)


 Agreed to add Hematologist as prescriber with restrictions.
 
 4)

 Ketoprofen 30mg Transdermal Patch 

 Rejected.

 
 5)

 Cefuroxime 4mg/0.4mL Intracameral Injection
 

 Accepted as Standard Formulary.

 
 6)

 Sodium Picosulfate 10mg Magnesium Oxide 3.5gm
 Anhydrous Citric Acid 12gm
 (Pico-Salax)
 

 Accepted as Standard Formulary for pediatrics only.

 
 7)

 Naltrexone 50mg Tablet
 

 Deleted.

 
 8)

 Peg-Filgrastin 6mg/0.6mL Injection
 (Peglasta)
 

 Deleted.

 
 9)

 Imipenem 500mg Cilastatin 500mg Injection
 

 Deleted.


Disclaimer: 
For new drug request, physical stock availability will depend on procurement processes. 
Tender items will take about 3-6 months, non tender items will take about 1-3 months. 
Online formulary will be updated once physical stock is available or has depleted in UMMC Pharmacy.

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