3.10 - Skin and Soft Tissue Infection [updated]

Ref: Stevens et al. Clin Infect Dis 2014; 59 (2): e10

Mild: Localized infection. Incision and drainage indicated. Oral antibiotic can be used if size of abscess is >5cm or surrounding erythema is >5cm.

Moderate: Evidence of systemic signs of infection, or extensive lesions. Incision and drainage indicated. Oral or systemic (IV) antibiotics can be used.

Severe: Evidence of severe sepsis or septic shock OR immunocompromised. Incision and drainage indicated. IV antibiotics should be used.

Non-purulent SSTI

Mild: Localised infection with no evidence of purulence. Oral antibiotics can be used.

Moderate: Evidence of systemic signs of infection, or extensive lesions. Oral or IV antibiotics can be used

Severe: Evidence of severe sepsis or septic shock, clinical signs of deeper infection, organ dysfunction OR immunocompromised. IV antibiotics should be used.

Consider IV antibiotic if there are multiple abscesses or extremes of age or lack of response to incision and drainage alone.

Antibiotic allergy refers to a true hypersensitivity reaction (immediate or delayed). Gastrointestinal symptoms are usually side effects and NOT a true allergy.

A) Adults

B) Paediatrics