NPRA Safety Alerts
(Year 2022)
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UMMC Antimicrobial Guidelines, 3rd Edition (2024) is now available!
21-Dec-2022 (No. SP PPUM: 573/2022)
Pneumococcal Polysaccharide Vaccine (23-Valent)
Pneumococcal Polysaccharide Vaccine (23-Valent)
Extensive Swelling of Vaccinated Limb
12-Dec-2022 (No. SP PPUM: 557/2022)
Sorafenib
Sorafenib
Risk of Thrombotic Microangiopathy (TMA)
07-Dec-2022 (No. SP PPUM: 549/2022)
Hydroxychloroquine and Chloroquine
Hydroxychloroquine and Chloroquine
Risk of Hepatic Impairment
17-Nov-2022 (No. SP PPUM: 511/2022)
Summary Report on Adverse Events Following Immunisation of COVID-19 Vaccines in Malaysia #5
Summary Report on Adverse Events Following Immunisation of COVID-19 Vaccines in Malaysia #5
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English Version
Versi Bahasa Malaysia
08-Nov-2022 (No. SP PPUM: 481/2022)
Piperacillin
Piperacillin
Risk of Haemophagocytic Lymphohistiocytosis (HLH)
04-Nov-2022 (No. SP PPUM: 477/2022)
COVID-19 Vaccines
COVID-19 Vaccines
Risk of Tinnitus
31-Oct-2022 (No. SP PPUM: 468/2022)
Iodinated Contrast Media
Iodinated Contrast Media
Risk of Hypothyroidism (Particularly in Newborns and Young Children)
25-Oct-2022 (No. SP PPUM: 452/2022)
Labetalol
Labetalol
Risk of Nipple Pain and Raynaud's Phenomenon of the Nipple
19-Oct-2022 (No. SP PPUM: 446/2022)
Sertraline
Sertraline
Risk of Microscopic Colitis
07-Oct-2022 (No. SP PPUM: 434/2022)
Nirmatrelvir / Ritonavir (PAXLOVID)
Nirmatrelvir / Ritonavir (PAXLOVID)
Risk of Anaphylaxis and Hypersensitivity Reactions
04-Oct-2022 (No. SP PPUM: 422/2022)
Alectinib (AlecensaⓇ)
Alectinib (AlecensaⓇ)
Risk of Haemolytic (New Warning and Precaution and Dose Modification Guidance)
30-Sep-2022 (No. SP PPUM: 417/2022)
Metformin
Metformin
Risk of Vitamin B12 Deficiency
10-Aug-2022 (No. SP PPUM: 330/2022)
Summary Report on Adverse Events Following Immunisation of COVID-19 Vaccines in Malaysia #4
Summary Report on Adverse Events Following Immunisation of COVID-19 Vaccines in Malaysia #4
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25-Jul-2022 (No. SP PPUM: 313/2022)
Corticosteroids (Systemic)
Corticosteroids (Systemic)
Risk of Pheochromocytoma Crisis
22-Jul-2022 (No. SP PPUM: 306/2022)
Chloroquine and Hydroxychloroquine
Chloroquine and Hydroxychloroquine
Risk of Psychiatric Disorders
21-Jul-2022 (No. SP PPUM: 304/2022)
Azathioprine
Azathioprine
Risk of Erythema Nodosum
24-Jun-2022 (No. SP PPUM: 260/2022)
Loperamide
Loperamide
Risk of Acute Pancreatitis
23-Jun-2022 (No. SP PPUM: 255/2022)
Olmesartan
Olmesartan
Risk of Autoimmune Hepatitis
14-Jun-2022 (No. SP PPUM: 244/2022)
Mavenclad® (Cladribine)
Mavenclad® (Cladribine)
Risk of Serious Liver Injury and New Recommendations About Liver Function Monitoring
18-May-2022 (No. SP PPUM: 192/2022)
Safety Updates on Covid-19 Vaccines
Safety Updates on Covid-19 Vaccines
Risk of Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT) / Thrombosis with Thrombocytopenia Syndrome (TTS)
12-May-2022 (No. SP PPUM: 183/2022)
Warfarin
Warfarin
Risk of Anticoagulant-Related Nephropathy (ARN)
10-May-2022 (No. SP PPUM: 174/2022)
Hydrochlorothiazide, Chlorthalidone, Indapamide and Acetazolamide
Hydrochlorothiazide, Chlorthalidone, Indapamide and Acetazolamide
Risk of Choroidal Effusion, Acute Myopia and Acute Angle-Closure Glaucoma
09-May-2022 (No. SP PPUM: 173/2022)
Summary Report on Adverse Events Following Immunisation of COVID-19 Vaccines in Malaysia #3
Summary Report on Adverse Events Following Immunisation of COVID-19 Vaccines in Malaysia #3
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08-Apr-2022 (No. SP PPUM: 130/2022)
Betamethasone (Systemic)
Betamethasone (Systemic)
Risk of Pheochromocytoma Crisis
24-Mar-2022 (No. SP PPUM: 110/2022)
Tenofovir Alafenamide
Tenofovir Alafenamide
Risk of Acute Renal Adverse Effects
22-Mar-2022 (No. SP PPUM: 105/2022)
Summary Report on Adverse Events Following Immunisation of COVID-19 Vaccines in Malaysia #2
Summary Report on Adverse Events Following Immunisation of COVID-19 Vaccines in Malaysia #2
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20-Jan-2022 (No. SP PPUM: 025/2022)
Clindamycin
Clindamycin
Risk of Acute Renal Failure
20-Jan-2022 (No. SP PPUM: 020/2022)
Janus Kinase (JAK) Inhibitors in Rheumatoid Arthritis Patients
Janus Kinase (JAK) Inhibitors in Rheumatoid Arthritis Patients
Risk of Major Adverse Cardiovascular Events (MACE) and Malignancies [Excluding Non-Melanoma Skin Cancer (NMSC)]
15-Nov-2022 (No. SP PPUM: 499/2022)
Methadone
Methadone
Risk of Hypoglycaemia
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